Cofitachequi

Cofitachequi was a Mississippian paramount chiefdom centered on the Wateree River valley in present-day South Carolina. By 1400 its center at Talimeco competed with neighboring chiefdoms, including Ocute.

In 1540 Hernando de Soto's Spanish expedition entered Cofitachequi; by Juan Pardo's visit in 1566 its regional power had diminished. Cofitachequi disappeared from the written record after 1670, following slave raids in the region.