Issati
The Issati is the name for the peoples of the Cofitachequi country in central South Carolina, a Mississippian chiefdom on the Wateree River with towns such as Talimeco and Hymahi. Visited by Hernando de Soto in 1540 and Juan Pardo in 1566, it was destroyed by seventeenth-century slave raids and vanished after 1670, its descendants absorbed into the Catawba.