Anna Komnene Doukaina Palaiologina Asanina

Anna Komnene Doukaina Palaiologina Asanina was a Byzantine noblewoman of the early fourteenth century, a daughter of the protostrator Theodore Synadenos and Eudokia Doukaina Komnene. In December 1321, at Adrianople, she married Manuel Komnenos Raoul Asanes, grandson of the Bulgarian tsar Ivan Asen III and brother-in-law of John VI Kantakouzenos.

She is portrayed beside her husband in a family miniature in the typikon of the Constantinople convent of Bebaia Elpis, founded by her grandmother Theodora Synadene. Her son Andronikos Asanes, raised by Kantakouzenos, later became sebastokrator.