Irene Laskarina
Irene Laskarina (c. 1194–1240) was a daughter of Theodore I Laskaris, founder of the Empire of Nicaea. She first married Andronikos Palaiologos; after his death her father in 1212 wedded her to his successor, the future John III Vatatzes.
When John succeeded in 1221 she became empress of Nicaea, and their son was Theodore II Laskaris. Badly injured in a riding accident after his birth, she could bear no more children, withdrew to a convent as the nun Eugenia, and died there in 1240.