Eugenia Palaiologina Kantakouzene

Eugenia Palaiologina Kantakouzene (1255–1329) was a Byzantine noblewoman of the Palaiologos and Kantakouzenos houses. Her mother Irene Palaiologina was a sister of Emperor Michael VIII, making Eugenia the emperor's niece. She married Syrgiannes, a Cuman chieftain baptized at court who rose to megas domestikos under Andronikos II.

Their son Syrgiannes Palaiologos became the turncoat general of the Byzantine civil wars of the 1320s and 1330s, while their daughter Theodora married Guy de Lusignan and became queen of Armenian Cilicia. Eugenia ended her life as a nun.