Irene Doukaina
Irene Doukaina (c. 1066–1138), empress of Alexios I Komnenos, was the daughter of Andronikos Doukas. She married Alexios in 1078, and her Doukas kin backed his 1081 seizure of the throne and secured her coronation. Long overshadowed by her mother-in-law Anna Dalassene, she accompanied him on campaign and acted as regent.
She pressed Alexios to set aside their son John in favour of Anna Komnene and Nikephoros Bryennios. After Alexios died in 1118 her plot against John II failed, and she ended her life in the nunnery she founded, dying in 1138.