Irene Palaiologina
Irene Palaiologina was the eldest daughter of Emperor Michael VIII Palaiologos and Empress Theodora. In 1277 or 1278 her father married her to the Bulgarian exile Ivan Asen III and sent armies to place him on the throne at Tarnovo during Ivaylo's revolt. Irene was crowned empress in 1279, but in 1280 the couple fled Tarnovo and returned to Constantinople.
In 1305 she plotted against her brother Andronikos II to avenge her son-in-law. The plot failed and she was placed under house arrest.