Jeguakava
Jeguakava lies in the Guaraní country east of the Uruguay River. In 1626 the Jesuit Roque González established São Nicolau, a mission settlement on the Piratini. Raids by bandeirantes forced its people to abandon the first settlement in 1637; São Nicolau was founded again nearby in 1687. Guaraní communities later resisted the transfer of the missions under a treaty between Spain and Portugal, and war followed in the 1750s.