Ofo

The Ofo, also called Mosopelea or Ofogoula, were a Siouan-speaking people whose villages stood on the upper Ohio River between the Muskingum and Scioto rivers. The Miami-Illinois name for the Ohio River, Mosopeleacipi, means river of the Mosopelea.

In the early 1670s, during the Beaver Wars, the Seneca and other Haudenosaunee nations overran their towns, and the Ofo fled down the Mississippi, staying briefly with the Quapaw before joining the Tunica. Around 1700 French travelers found them on the Yazoo River. After refusing to join the Natchez wars against the French they moved south into Louisiana, where the remnant band merged with the Tunica and Biloxi and their Siouan-Catawban language fell extinct.