Yamasee
The Yamasee were a multiethnic confederation formed from displaced peoples of the Georgia region. Spanish records first named them in 1663.
In the 1680s they settled near the Savannah River and allied with South Carolina, trading Indian captives for firearms. In 1715 the Yamasee and other peoples attacked the colony, threatening its survival; the Yamasee were defeated and dispersed, and survivors joined other tribes.