Otatitlan
Otatitlan was a river settlement on the lower Papaloapan, between Veracruz and Oaxaca. Before the Spanish conquest its Popoluca inhabitants used it as a trading post on the Gulf lowlands' river routes.
During the colonial period its population changed from Popoluca to Mazatec. Jesuit missionaries established the mission of San Ignacio Otatitlan. Under Viceroy Diego Fernandez de Cordoba the town was refounded and dedicated to Saint Andrew, becoming known in colonial records as San Andres Otatitlan. It acquired municipal status in 1831.