Città di Castello
Città di Castello was a commune in the upper Tiber valley of northern Umbria. Around 1337 it was held by Guido and Pier Saccone da Pietramala, who had seized it in 1332.
From 1440 the city leaned on Florentine protection. Niccolò Vitelli survived a sixty-seven-day siege by papal troops in 1474 and returned as recognized lord in 1482. After Vitellozzo Vitelli’s execution in 1502, Cesare Borgia seized the city, which later came under papal government.