Stefan Uroš V
Stefan Uroš V (1336–1371), called the Weak, was the only son of Stefan Dušan and Helena of Bulgaria. Crowned co-ruler in 1346, he succeeded as Serbian emperor in 1355, under whom the empire broke apart: his uncle Simeon Uroš proclaimed himself tsar, his mother Helena held Serres, and magnates such as Nikola Altomanović ruled on their own.
In 1365 Vukašin Mrnjavčević became co-ruler and in 1369 made his son Marko heir. After the Maritsa disaster of 1371, Uroš died childless that December, ending Nemanjić rule; he was canonised.