Anna of Saxe-Wittenberg

Anna of Saxe-Wittenberg (c. 1290–1327) was a German noblewoman of the House of Ascania, the daughter of Duke Albert II of Saxony and Agnes of Austria, herself a daughter of King Rudolf I of Germany. On 6 July 1315 she married Henry II the Lion, Lord of Mecklenburg, as his second wife.

Her children included Albert II the Great, the first Duke of Mecklenburg, and John I of Mecklenburg-Stargard. She died in November 1327.