Francesco di Giovenco de' Medici

Francesco de' Medici was the youngest son of Giovenco de' Medici, one of the six Medici brothers who founded the family's Florentine bank, the compagnia filii Averardi. He married Francesca di Gregorio Dati, and their son Tommaso continued the line.

His descendants formed the patrician branch called the Medici di Lungarno, which died out in the male line in 1793 and in the female line in 1859, and from which the Florentine Lenzoni family descended through the female line.