Thomais Orsini

Thomais Komnene Angelina, better known as Thomais Orsini (c. 1330 – before 1385), was the daughter of John II Orsini, Despot of Epirus, and Anna Palaiologina. In 1335 her father died of poison, and in 1338 Emperor Andronikos III annexed Epirus, driving her family from Arta.

Around 1348 she married the Serbian governor Simeon Uroš, half-brother of Stefan Dušan. After her brother Nikephoros II died in 1359, Simeon ruled both Epirus and Thessaly. Her children included John Uroš of Thessaly and Maria, wife of Thomas II Preljubović.