Anna Palaiologina
Anna Palaiologina (c. 1302–1320) was a Byzantine princess, daughter of co-emperor Michael IX Palaiologos and Rita of Armenia. In 1304 the Epirote regent Anna Palaiologina Kantakouzene sought her for her son Thomas I Komnenos Doukas; they married around 1307, tying the Despotate of Epirus to Constantinople. Sources hint that Thomas treated her badly.
In 1318 Thomas was murdered by his nephew Nicholas Orsini, who seized Epirus and, though she was technically his aunt, took Anna as his wife. She died two years later, in 1320.